Gumtree India Analytical

HPLC with UV detection is a widely used and accepted analytical technique. However, there are times when the lack of a chromophore is limiting. To address this problem some laboratories have turned to Mass Spec. But not all compounds ionize readily and the response of those that do can vary widely. Refractive Index detection lacks sensitivity, can not be used with gradient and is often difficult to operate due to drift and instability. Evaporative Light Scattering Detection accommodates gradient HPLC but suffers from fundamental limitations imposed by the physics of light scattering.